The Gunners manager switched to a 3-4-2-1 formation for the Gameweek 33 win at Middlesbrough, with Alexis Sanchez (£11.5m) and Mesut Ozil (£9.4m) handed central support roles behind Olivier Giroud (£8.1m).
Having failed to find the net in his previous three Gameweek appearances, Sanchez was back on the scoresheet in that match to return to the top of the FPL player standings.
See: FPL player standings
Owned by only 6.1% of FPL managers, Ozil’s winner took his tally to two goals and a pair of assists from his previous four Gameweek appearances.
Despite the revival from Sanchez, only just over 5,000 FPL managers have transferred him in ahead of a Gameweek 35 derby match with Tottenham Hotspur.
But Arsenal then play four fixtures over the next two Gameweeks, with encounters against Manchester United and Southampton in Gameweek 36 followed by promising match-ups against Stoke City and Sunderland in Gameweek 37.
That ensures Sanchez will become a hot property and an obvious captaincy contender for those two Gameweeks.
Playing as wing-backs in each of Arsenal's last two matches, they grabbed a goal and assist respectively in the FA Cup victory over Man City to suggest they could emerge as differential picks.
Sitting in 3.3% of FPL squads, Monreal had returned only two assists in the opening 33 Gameweeks, while Oxlade-Chamberlain has dropped to 1.2% ownership on the back of a single assist from Gameweek 16 onwards.
Oxlade-Chamberlain will undergo a fitness test ahead of Wednesday's home meeting with Leicester City, having picked up a knock on Sunday.
Elsewhere, Wenger's switch to a three-man central defence has afforded Rob Holding (£4.0m) and Gabriel (£4.8m) consecutive appearances alongside Laurent Koscielny (£6.1m) in the absence of the injured Shkodran Mustafi (£5.8m).
Holding would appear the most likely to make way should Mustafi earn a recall. However, after impressing in his new role, Gabriel may have cemented his starting berth to offer FPL managers a budget-friendly route into the Gunners' defence over the busy run-in.