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Newcastle have lost only one of their last 16 Premier League home matches against Southampton (W12 D3), winning the last four against Saints at St James' Park.
Only Trent Alexander-Arnold (10) has created more chances in the opening two Premier League matches this season than Newcastle's Matt Ritchie (9). He created four chances against West Ham and five against Aston Villa.
Southampton's Theo Walcott has been involved in more Premier League goals (11) against Newcastle than he has any other side in the competition (five goals, six assists). Five of these goal involvements came in a single match in December 2012 (three goals, two assists).
Saints have lost 11 of their last 12 Premier League matches on the road (W1), including each of the last six. They last lost seven consecutive away league matches between November 2004 and February 2005, in the season they were relegated from the top flight.
Match officials
Referee: Paul Tierney. Assistants: Constantine Hatzidakis, Ian Hussin. Fourth official: John Brooks. VAR: Mike Dean. Assistant VAR: Dan Robathan.