In attack, Ilkay Gundogan (£6.1m) has been their standout player in Fantasy of late.
The German has scored twice in three of his last six appearances, and totalled 70 points in his last seven outings.
Both Kevin De Bruyne (£11.8m) and Raheem Sterling (£11.6m) offer strong alternatives for the armband.
At home, De Bruyne’s 31 shots and 26 chances created are both team-leading totals.
Sterling, meanwhile, has blanked just once in his last six outings, scoring four goals and supplying two assists.
Man City’s strong defence should also be considered, having claimed 13 clean sheets in their last 17 Premier League contests.
Ruben Dias (£6.1m) is the defender who is least likely to be rotated, having started 22 of Man City’s last 23 matches.
Joao Cancelo (£6.1m) is their most attacking pick at the back. His 25 shots and 34 key passes both rank among the top five defenders in Fantasy this season.
John Stones (£5.2m), meanwhile, was their top-scoring player in Double Gameweek 19, bringing in 27 points.
His 57 shots in the box and 35 shots on target both rank among the top three players in Fantasy this season.
Dominic Calvert-Lewin (£7.7m) and Ollie Watkins (£6.5m) provide further armband options up front.
They are both among the bottom six sides for goals conceded this season, with 43 and 41 respectively.
Part 1: GW26 Kings to watch: Calvert-Lewin has fixtures to thrive
Part 2: GW26 Differentials: Traore a key figure for Villa
Part 3: GW26 Captains: Fernandes can extend goal streak
Part 5: Who to captain in Double GW26? What the experts say
Part 6: Scout Selection: Digne part of Everton double-up
Part 7: GW26 final call: Jota can make Double Gameweek impact
Remember, the Gameweek 26 deadline is at 11:00 GMT on Saturday 27 February.