Tottenham Hotspur midfielders Victor Wanyama (knee) and Mousa Dembele (both hips) are out. Erik Lamela will likely not feature as he continues to build up his fitness.
Ben Davies and Georges-Kevin NKoudou have returned to full training.
Liverpool are again without Sadio Mane (hamstring), Adam Lallana (thigh) and Nathaniel Clyne (back).
Did you know?
After a run of four wins and a draw between 2010 and 2012, Tottenham Hotspur are winless in their last nine Premier League matches against Liverpool (W0 D3 L6).
Wembley Stadium could become the 53rd different ground that Liverpool have won a Premier League match at, extending their own current record of 52.
There have been a Premier League record of nine own goals scored in this fixture.
Harry Kane has not scored in either of his PL home appearances v Liverpool (173 mins); the only side he has faced more often without finding the net at home in the competition is Crystal Palace (three apps, 269 mins).
What the managers say
Mauricio Pochettino: We have a lot of good games, a lot of exciting games, but we are taking it step by step and now it's Liverpool.”
See: Winks' journey back
Jurgen Klopp: I’m really looking forward to this game because you don’t have a lot of these games where both teams are going for everything.
Referee: Andre Marriner
Assistants: Simon Beck, Scott Ledger
Fourth official: Mike Jones
