Lying 10 points behind leaders Manchester City with a match in hand, Manchester United need at least a point against Leicester City to stay in the title race.
Leicester are seeking to consolidate their top-four status, and a victory at Old Trafford would take them up to third ahead of their final two fixtures against Chelsea and Spurs.
Team news
Did you know?
Man Utd are unbeaten in their last 12 Premier League matches against Leicester (W8 D4).
With five strikes, Man Utd’s Marcus Rashford has scored more PL goals versus Leicester than he has against any other side in the competition.
Leicester have scored in 15 of their 17 PL away matches this season, with no side finding the net in more contests on the road.
Leicester striker Kelechi Iheanacho has been directly involved in five goals in five starts against Man Utd in all competitions, with three strikes and two assists. He scored twice and set up a goal in a 3-1 win over the Red Devils in the FA Cup earlier this season.
Match officials
Referee: Craig Pawson. Assistants: Ian Hussin, Richard West. Fourth official: Mike Dean. VAR: Jonathan Moss. Assistant VAR: Marc Perry.