Football writer Adrian Clarke looks at key tactical points and players who can be decisive in Matchweek 37.
Team analysis: Chelsea
Chelsea head coach Enzo Maresca has some big decisions to make ahead of a hugely important home match against Manchester United on Friday night.
Viewed as a must-win if the Blues are to achieve a top-five finish, the Italian must find a solution up front with Nicolas Jackson suspended for the final two matches of the campaign.
Chelsea are already light on numbers in attack with on-loan Jadon Sancho also unable to face his parent club.
So, what will Maresca opt to do?
Attacking options
There is not too much selection wriggle room for the head coach with Marc Guiu and Christopher Nkunku also unavailable.
If Maresca opts to stick with his favoured 4-2-3-1, he could perhaps lean towards employing Pedro Neto up front.
In that shape, Noni Madueke and Cole Palmer may be used out wide, with Enzo Fernandez pushed up into the No 10 role.
Alternatively, could we see 19-year-old academy graduate Tyrique George come in for his full Premier League debut?
This would see Neto play wide, and Palmer staying put behind the main striker.
The third option would see Maresca revert to the 4-3-3 he used most frequently as head coach at Leicester City in the Championship.
In that shape we would likely see Neto as striker, flanked by Madueke and Palmer, with Romeo Lavia, Fernandez and Moises Caicedo operating behind in a midfield three.
George has earned Maresca's trust
Teenage forward George has been with Chelsea since the age of eight, and has impressed in his breakthrough season in the first team.
He has made 23 appearances across all competitions so far, with the bulk of those coming in the UEFA Conference League.
The forward scored his first senior goal at Legia Warsaw last month, calmly tucking home a rebound with his weaker left foot from close range.
But it was George’s first Premier League goal that caught the eye most however, firing a fierce drive into the bottom corner from 19 yards out in the west London derby against Fulham.
His clean strike emphasised his excellent technical ability.
George's goal v Fulham
George can operate wide on the right or left, as well as down the middle as a striker.
When playing as a centre-forward, his preferred style is to link play from pockets rather than running in behind the last man, like Jackson or Neto.
We have already seen snippets of real creativity from him.
He has proved he can make things happen, and has five key passes, including an assist, in just 97 minutes of game time in the Premier League.
His assist for Marc Cucurella at home to Southampton on 25 February saw him driving to the byline before cutting the ball back.
George's assist for Cucurella
He very nearly set Cucurella up for another goal from a near-identical situation in Chelsea’s 1-0 defeat at Arsenal.
If he does feature against Man Utd, keep an eye out for George flying down the right-side channel looking to send deliveries into the box.
It would be a bold option for Maresca to hand the academy graduate his first Premier League start in a match of such magnitude, but he could be a surprise package.
The teenager will not be fazed if he is asked to step up as he is blessed with a cool temperament and lots of ability.
Is Neto the answer?
While Jackson was injured across February and March, Maresca selected Neto to lead the line most frequently in his absence.
He did experiment with Nkunku, but the closest match style-wise to Jackson is the Portuguese international.
Neto looked sharp in patches during this period, but his only major contributions were a goal and an assist against Southampton, and an assist at Aston Villa.
His clever looping run around Nkunku against Saints opened up space for him to score with a rasping left-footed shot.
Neto's goal v Southampton
The former Wolverhampton Wanderers attacker does not make quite as many runs as Jackson, but he is undoubtedly the next most mobile option for Chelsea in that position.
Jackson is inside the division’s top 10 for most categories revolving around dynamic runs, but Neto is not too far behind him.
Jackson and Neto's PL running stats ranked 24/25
| Jackson | PL rank | Neto | PL rank | |
| Runs* | 32.01 | 4th | 29.86 | 12th |
|---|---|---|---|---|
| Sprints** | 25.46 | 4th | 23.56 | 11th |
| Runs into box* | 9.01 | 9th | 7.15 | 27th |
| Runs targeted by pass* | 11.18 | 6th | 10.24 | 11th |
*Min 20 starts|**Min 1,000 minutes
Maresca will opt for the speedy 25-year-old if he wants a like-for-like replacement against Man Utd.
Neto’s top speed this season has been clocked at 35.4km/hr, ranking him 27th in the Premier League, with only Mykhailo Mudryk ahead of him in the Chelsea squad.
This brilliant, arced run at Villa showcased the value of Neto’s speed and intelligent movement.
Sensing that the left-back space was vacated, he bent a run into that channel to perfection to offer himself for a longer pass.
From this run he surged down the wing before crossing for midfielder Fernandez to score.
Neto favourite to get the nod
While there is a possibility Maresca will take a chance of using George as his main striker on Friday, it is more probable that Neto will be handed that responsibility, from the start at least.
Neto’s record when starting as a striker in Premier League matches - for Wolves and for Chelsea - is not hugely impressive.
He has four goals and five assists from 33 matches this season, but his skillset does match what Maresca is looking for from his No 9.
An attacking midfield trio of Madueke, Fernandez and Palmer behind Neto feels like the most potent attacking line-up available in a contest they need to win.
Chelsea's promising young forward George could be the impact change the team needs later in the match.