After three consecutive defeats, 14th-placed Crystal Palace are aiming to reignite their hopes of a top-half finish.
Chelsea could leapfrog Leicester City into third place with an away win in this London derby.
Martin Kelly (calf) is back in training for Palace, but this match is likely to come too soon for the defender. James Tomkins, while Jeffrey Schlupp remains out.
Chelsea midfielder N'Golo Kante (hamstring) will miss the trip to Selhurst Park, joining Mateo Kovacic (Achilles) and Fikayo Tomori (muscle problem) on the sidelines.
Palace are the only unbeaten side in home Premier League London derbies this season. If they are defeated here, every London side will have lost a home derby in the competition for the first time since 2012/13.
None of the last 17 Premier League meetings between the Eagles and Chelsea have finished level, with the Blues winning 13 to Palace’s four.
Chelsea have won four of their last five Premier League matches, as many as in their previous 13, and have scored at least twice in nine of their last 10 fixtures.
Against Watford, Willian became just the sixth player to score a penalty in three consecutive Premier League appearances. He can now become the first to make it four in a row.
Referee: David Coote. Assistants: Neil Davies, Nick Hopton. Fourth official: James Linington. Replacement official: Andrew Laver. VAR: Peter Bankes. Assistant VAR: Ian Hussin.