Jose Mourinho is looking for a response after suffering his first defeat as Tottenham Hotspur head coach against Manchester United, and a win could move Spurs back into the top six.
Burnley are seeking their second away win of the season, with their first coming against Watford in their previous road trip.
Team news
Spurs suffered no new injuries at Old Trafford and so Ben Davies, Erik Lamela, Hugo Lloris and Michel Vorm are their only absentees.
Ashley Barnes (groin) is likely to be available for Burnley, but Charlie Taylor, Phil Bardsley and Kevin Long are all doubts.
Ashley Westwood is eligible again after serving a suspension against Manchester City but is a doubt due to a groin injury. Johann Gudmundsson (hamstring) remains out.
Did you know?
Spurs have won seven of their last eight home meetings with Burnley in all competitions since a 4-1 League Cup defeat in January 1983.
Son Heung-min has been directly involved in 13 goals in his 14 appearances at Tottenham Hotspur Stadium in all competitions, with eight strikes and five assists, more than any other player.
Burnley beat Spurs 2-1 in the last Premier League meeting at Turf Moor in February. They last won consecutive top-flight matches against them back in April 1975.
The Clarets won 3-0 against Watford in their last away league match. They have not won consecutive league matches on the road since a run of three victories in April 2018.
Match officials
Referee: Kevin Friend. Assistants: Adrian Holmes, Mark Scholes. Fourth official: Robert Jones. VAR: Lee Mason. Assistant VAR: Dan Robathan.