The Argentinian has scored more Premier League goals against the Blues than any other player in the competition's history, finding the net 10 times.
Indeed, Aguero has netted eight goals in his last six matches against Chelsea, including a hat-trick in this exact fixture last season.
So, supporters of other Premier League clubs, who do you think has been the nemesis of your team?
Well, Chelsea are not the only side to have suffered at the hands of Aguero.
They were the arch-rival of as many as five current Premier League clubs.
|Aston Villa||Frank Lampard, Wayne Rooney||13|
|AFC Bournemouth||Raheem Sterling||9|
|Crystal Palace||Jermain Defoe||9|
|Everton||Les Ferdinand, Alan Shearer||16|
|Man City||Alan Shearer||11|
|Man Utd||Alan Shearer||10|
|Newcastle||Sergio Aguero, Wayne Rooney||15|
|Sheff Utd||Kevin Campbell, Tony Cottee, Robbie Fowler, Mark Hughes,
Wayne Rooney, Teddy Sheringham, Yakubu
|West Ham||Wayne Rooney||14|