Both sides are aiming to build momentum after ending a winless run with a victory last time out.
Watford have moved off the foot of the table and sit three points behind 17th-placed Aston Villa, while Burnley's 3-0 home win over West Ham United in their latest outing took them into the top half of the table.
Team news
Watford duo Troy Deeney and Ismaila Sarr could be named together in the squad for the first time after both took part in training this week.
However the Hornets are unable to call on Domingos Quina (groin), Tom Cleverley (heel), Daniel Bachmann (hamstring), Danny Welbeck (hamstring), Sebastian Prodl (knee) and Roberto Pereyra (hamstring), while Christian Kabasele is suspended.
Burnley's Matej Vydra (hip) is unlikely to be involved against his former club while Johann Berg Gudmundsson (hamstring) and Danny Drinkwater (ankle) remain sidelined.
Did you know?
Watford's win at Norwich City last time out ended a run of 15 Premier League matches without a win (D6 L9). The Hornets are now looking to secure back-to-back league victories for the first time since February.
After a run of 10 matches and 26 shots without a top-flight goal, Watford's Gerard Deulofeu has netted with two of his last four attempts and is looking to score in three consecutive Premier League appearances for the first time.
Since the start of last season, Burnley's Chris Wood has scored nine headed goals, more than any other player in the Premier League. Three of the New Zealander's five goals this season have been scored this way.
Burnley have lost just one of their last five away league fixtures at Vicarage Road, although three of those matches have been drawn.
Match officials
Referee: Paul Tierney. Assistants: Daniel Cook, Harry Lennard. Fourth official: Jarred Gillett. VAR: Peter Bankes. Assistant VAR: Marc Perry.