West Bromwich Albion dented Southampton’s title hopes in Premier League 2 Division 2 and set up an exciting finale to the season.
A Southampton victory would have sent them top and put their fate in their own hands ahead of the final round of fixtures.
They took the lead through Will Smallbone's 48th-minute penalty.
Wolves and Reading play first, facing trips to Manchester United and Stoke City respectively on 26 April.
Southampton will take on Division 2's bottom side Sunderland three days later, knowing what they need to do to get the sole automatic promotion place. If unsuccessful, they will enter the promotion playoffs.
See: Southampton report