Goalkeeper Adrian will return to West Ham United's starting line-up as Joe Hart is ineligible to face his parent club.
Manuel Lanzini is pushing for a place in the team while Pedro Obiang (knee), Winston Reid (knee), James Collins (hamstring), Sam Byram (ankle) and Michail Antonio (hamstring) remain out.
Fernandinho is available for Manchester City after completing a suspension but Sergio Aguero (knee) remains sidelined.
Did you know?
West Ham United have lost only one of their last seven Premier League home matches (W3 D3), going down 3-0 to Burnley last month.
Manchester City have won their last two PL matches played in London, beating Arsenal and Tottenham Hotspur. They have not won three consecutive top-flight matches in the capital since January 1955.
Man City are one victory away from equalling Chelsea's record of 30 wins in a single PL season. If they score two goals they will become the fourth and fastest side to reach 100 goals in one campaign (35 matches).
David Silva and Leroy Sane are one goal away from joining Sergio Aguero, Raheem Sterling and Gabriel Jesus in double figures in the Premier League this season. No side have had five players reach double figures for goals in the same season in the competition's history.
Club previews
West Ham: Moyes: We'll need all the fans
Man City: Guardiola: A joy to have Mendy back
Referee: Neil Swarbrick
Assistants: Scott Ledger, Marc Perry
Fourth official: Bobby Madley
