Tottenham's Hotspur's Jan Vertonghen (ankle) has returned to training but Toby Alderweireld (hamstring) is still working alone and is unavailable.
Huddersfield Town's Philip Billing has recovered from illness but Aaron Mooy (knee) will not be back in full training until next week.
Elias Kachunga and Jon Gorenc Stankovic (both knee) are long-term absentees.
Did you know?
Tottenham Hotspur have won their last 15 matches against promoted sides, the third-longest run in PL history after Chelsea (27 between 2002 and 2006) and Manchester United (17 between 2006 and 2009).
Spurs are currently on the Premier League’s longest unbeaten run (10 matches, W7 D3 L0), last losing at Manchester City in December.
Huddersfield Town have the chance to secure a third successive PL victory for the first time. They last achieved that in a top-flight campaign in April 1956 (four in a row).
If Harry Kane scores, he will be the third player to score 25+ goals in three consecutive PL seasons, after Alan Shearer (four seasons between 1993/94 and 1996/97) and Thierry Henry (three seasons between 2003/04 to 2005/06).
Club previews
Tottenham Hotspur: Pochettino: The latest on Vertonghen
Huddersfield Town: Wagner: We go to Wembley with positive memories
Referee: Mike Jones
Assistants: Ian Hussin, Mark Scholes
Fourth official: Kevin Friend