Southampton defenders Ryan Bertrand (hamstring) and Cedric Soares (ankle) are out.
Huddersfield Town are without Elias Kachunga (knee), Michael Hefele (Achilles), Jonathan Hogg (suspended) and Philip Billing (ankle).
Did you know?
Southampton have won their last three home matches against Huddersfield Town in all competitions, scoring 13 goals and conceding only once.
Saints have lost only one of their last 26 home Premier League matches against promoted sides (W17 D8).
Huddersfield Town's 4-1 win at Watford in Matchweek 18 ended a run of seven consecutive away PL matches without a goal (D1 L6).
Charlie Austin has been directly involved in six goals in seven previous league appearances against the Terriers (four goals, two assists).
What the managers say
Mauricio Pellegrino: "We have got the same feeling as the fans when we play badly. We are unhappy and we have to try to bounce back from these situations and show our best version to them."
See: Bertrand out for Huddersfield match
David Wagner: "Southampton is a team full of top-class individuals and has a very good manager, but we have to be clear on getting all of our details right and being focused on us."
See: Zanka: When we are at our best
Referee: Lee Probert
Assistants: Simon Beck, Andy Garratt
Fourth official: Keith Stroud
