After three minutes Alexandre Lacazette latched on to a neat flick from Aaron Ramsey to fire in his seventh goal of the season.
Petr Cech denied Collin Quaner with fine reaction save before Arsenal struck three times in four second-half minutes.
Olivier Giroud, a half-time replacement for Lacazette, connected with Mesut Ozil’s through-ball to double the lead on 68 minutes. Moments later Ozil teed up a neat Alexis Sanchez strike.
Then Ozil was picked out by Ramsey to dink the ball into the back of the net, leaving Giroud to confirm the three points with a late close-range effort.
Arsenal: 2 Dec v Man Utd (H)
Huddersfield: 2 Dec v Everton (A)