Liverpool moved five points clear of Everton at the top of Division 1 after a 3-1 win over bottom club Manchester United in front of a crowd of 4,557 at Leigh Sports Village.
A strong Liverpool side, including Danny Ings, Trent Alexander-Arnold, Marko Grujic and Jon Flanagan, went ahead in the 14th minute through Ovie Ejaria.
Joshua Bohui set up James Wilson to equalise for United on the hour mark, but Grujic quickly restored Liverpool's lead by heading in Ben Woodburn's corner.
Harry Wilson wrapped up their seventh win in eight matches with a fierce shot.
Both teams play again on Sunday 29 October with United, who are two points adrift of 11th-placed Chelsea, facing Sunderland at Eppleton Colliery Welfare Ground and Liverpool hosting Leicester City at Tranmere.
See: Man Utd report | Liverpool report
The first of #LFCU23s' three goals in their #PL2 clash with Manchester United last night...— Liverpool FC (@LFC) October 24, 2017
Highlights: https://t.co/xDgSdK5hr7 pic.twitter.com/4bJQ0TgTWB