As Fantasy Premier League managers can now select their 15-man squads, The Scout analyses standout budget and premium players in each position.
Three favourable home matches in the first five Gameweeks lifts the prospects of Manchester City's key players.
According to the Fixture Difficulty Ratings (FDR), two of those encounters score only two.
De Bruyne was a big success in his final two home appearances of 2020/21.
He scored three goals and supplied an assist in those matches against Southampton and Everton, with the champions netting five times on each occasion.
Although he managed only four goals at home last season, the underlying statistics reflect De Bruyne's influence as an attacking threat.
His 46 shots and 18 shots were both team-leading totals.
The Belgian’s creativity was also a major weapon for Pep Guardiola’s side.
He produced 45 key passes and eight assists at home, both more than any team-mate.
De Bruyne's £12.0m price has deterred many managers from bringing him into their opening squads.
Only 15.9 per cent have selected him compared to fellow midfield big-hitters Mohamed Salah (£12.5m) and Bruno Fernandes (£12.0m), who are owned by 49.7 per cent and 40.5 per cent respectively.
That marks De Bruyne out as a major alternative for the captaincy over Man City’s early home matches.
Tomorrow: The Scout on Bruno Fernandes