If West Ham United avoid defeat they will be guaranteed a sixth-placed finish and UEFA Europa League football, while defeat could result in them being overtaken on goal difference by both Tottenham Hotspur and Everton should they win.
Southampton could finish in 12th place if they win and other results go their way.
Team news
Did you know?
West Ham need a point to guarantee a top-six Premier League finish for only the second time, finishing fifth in 1998/99.
Michail Antonio's strike against West Bromwich Albion took him to 46 PL goals for the club, one behind Paolo Di Canio’s record of 47 which has stood since 2003.
Southampton have lost nine of their 10 PL away games in 2021, with the exception a 2-0 victory at Sheffield United.
If James Ward-Prowse plays 90 minutes in this match, he will be the first midfielder to play every minute in consecutive PL seasons.
Match officials
Referee: Martin Atkinson. Assistants: Constantine Hatzidakis, James Mainwaring. Fourth official: Matt Donohue. VAR: Andre Marriner. Assistant VAR: Peter Kirkup.
