Tottenham Hotspur have no fresh injury concerns, only Matt Doherty and Ben Davies are unavailable.
Manchester United will assess the fitness of Marcus Rashford and Luke Shaw. Anthony Martial (knee) remains sidelined.
Spurs can become the first team to record a Premier League double over Ole Gunnar Solskjaer's Man Utd side. It would also be Spurs' first PL double over the Red Devils.
Harry Kane needs one more goal to reach 20 PL strikes in a fifth different campaign. He would become just the fourth player to achieve the feat in the competition after Alan Shearer (seven times), Sergio Aguero (six) and Thierry Henry (five).
Man Utd are unbeaten in 22 PL away matches (W14 D8). Only Arsenal have registered longer such runs on the road, having a 23-match sequence between August 2001 and September 2002 and a 27-match run between April 2003 and September 2004.
Mason Greenwood is looking to score in consecutive PL appearances for the first time since July 2020, while only Wayne Rooney (15) and Marcus Rashford (13) have scored more PL goals as a teenager for Man Utd than Greenwood's 12.
Referee: Chris Kavanagh. Assistants: Adam Nunn, Sian Massey-Ellis. Fourth official: Andre Marriner. VAR: Craig Pawson. Assistant VAR: Harry Lennard.