Liverpool's Egyptian ended a run of six successive blanks to claim 15 points in the 3-1 win over West Ham.
Salah's potential may be raised further by doubts over the fitness of fellow winger Sadio Mane (£11.9m) for Liverpool's home match with Brighton & Hove Albion.
He seems to be more explosive in FPL when the Senegalese is not involved. Indeed, three of Salah's last four double-figure hauls have come when Mane has not played.
Despite managing only one assist in the last four Gameweeks, the Portuguese has remained a major goal threat.
Indeed, his 17 shots in that period were a league-leading total.
Ilkay Gundogan (£5.8m) is their most in-form player, with four double-figure hauls in his previous nine outings.
Meanwhile, Joao Cancelo (£6.0m), Raheem Sterling (£11.6m) and Riyad Mahrez (£8.1m) are all expected to return to the starting XI after being rested against Sheffield United.
Full-back Cancelo claimed 17 points in his last away outing, combining a goal and an assist with a clean sheet.
Sterling has improved his consistency in recent matches, producing attacking returns in six of his last seven starts.
And Mahrez has a prolific record against Burnley, scoring five goals in his last two meetings with them.
Midfield pair Harvey Barnes (£6.9m) and Jack Grealish (£7.7m) also boast strong form.
Grealish has blanked only once in five outings ahead of a home encounter with West Ham.
Callum Wilson (£6.7m) and Wilfried Zaha (£7.2m) can also reward managers in their head-to-head at St James' Park.
Crystal Palace talisman Zaha has recorded all three of his double-figure hauls this season away from home.
Part 1: GW22 Kings to watch: Grealish to extend run of returns
Part 2: GW22 Differentials: Hudson-Odoi starring for Tuchel
Part 4: Who to captain in GW22? What the experts say
Part 5: Scout Selection: Mahrez fresh to shine against Burnley
Remember, the Gameweek 22 deadline is at 16:30 GMT on Tuesday 2 February