Mohamed Salah (£12.5m) blanked for the fifth match in a row to make it an underwhelming Double Gameweek 19 (DGW) for the three most-popular Fantasy Premier League captains.
More than 1.2million managers had backed Salah with the armband, with 151,000 Triple-Captaining him, but the Egyptian was dropped for Liverpool's match against Burnley.
Salah came off the bench in the 1-0 loss but returned only one point to finish the Double Gameweek with a total of four points.
How the top 5️⃣ captains scored in GW19:— Fantasy Premier League (@OfficialFPL) January 22, 2021
1️⃣ Salah (1,278,283) - 4 points
2️⃣ De Bruyne (1,128,015) - 8 points
3️⃣ Fernandes (1,031,039) - 8 points
4️⃣ Kane (823,151) - 9 points
5️⃣ Son (576,880) - 5 points#FPL pic.twitter.com/CeUn0tamYW
That disappointment came after Kevin De Bruyne (£11.9m) was injured in Manchester City's win over Aston Villa on Wednesday.
It meant the Belgian did not add an attacking return to the assist and seven points he picked up in the first match of his Double Gameweek against Crystal Palace.
Coming off on 58 minutes, De Bruyne also missed out on a clean-sheet point. FPL managers will now have to plan without him for the Gameweek 20 trip to West Bromwich Albion, after Pep Guardiola confirmed he will be out for four to six weeks.
Owners of Bruno Fernandes (£11.3m) fared no better. After blanking in Sunday's 0-0 draw at Liverpool, the Manchester United midfielder was again unable to score at Fulham.
He did at least provide an assist to return eight points for the Double Gameweek and equal De Bruyne's tally.
|Player||Triple-Captained by ('000s)|
In total, 1,559,146 chips were used in Gameweek 19.
In addition to those playing their Triple Captain chip, more than 416,000 managers used their Wildcard, while over 387,000 activated their Bench Boost.
|Chip||Chips played ('000s)|
The leading 100 FPL managers favoured De Bruyne over Salah for the Gameweek 19 captaincy, with Jamie Vardy (£10.1m) ousting Fernandes in third.
Vardy also disappointed his backers by blanking against both Southampton and Chelsea, despite Leicester City scoring four goals in the process.
The Leicester striker also faces a spell on the sidelines as he is due to have minor surgery.
A combined 1,046,936 brought in one of West Ham United's Tomas Soucek (£5.3m) and Michail Antonio (£6.3m).
Antonio's new owners were delighted after he scored against both Burnley and West Brom, collecting the maximum bonus each time to rack up 18 points in total.
Those who opted for Soucek will be ruing that call as he blanked in both matches and was booked against Burnley, cancelling out his clean-sheet point.
Backers of Phil Foden (£6.3m) were also left frustrated.
More than 451,000 added him to their squads, but the 20-year-old claimed just one point off the bench for Man City against Palace and, despite a strong showing against Villa, managed only three further points.
|Player||Transferred in by ('000s)||Points|
The injured Dominic Calvert-Lewin (£7.6m) was the most-sold player for the second week in a row, shipped out by a further 1.3million managers. Everton are without a fixture this Gameweek.
FPL's highest points-scorer, Son Heung-min (£9.7m), was transferred out by more than half a million managers as attention turned to Double Gameweek players.
But Son's assist for Serge Aurier (£5.2m) in Tottenham Hotspur's 3-1 win at Sheffield United earned him five points.
More than 341,000 sold Pedro Neto (£5.9m), who was a doubt heading into the weekend and blanked as Wolverhampton Wanderers lost 3-2 to West Brom.
|Player||Transferred out by ('000s)||Points|
See: Fantasy Premier League stats
Part 2: GW19 Bonus points: Targett hits top spot
Part 3: FPL Saturday review: Pereira a powerful differential
Part 4: FPL Sunday review: Managers rushing to Stones
Part 5: Which players are on or close to suspension?
Part 6: FPL Monday review: Is there value in Aubameyang?
Part 7: FPL Tuesday review: Fixtures boost Maddison's appeal
Part 8: FPL Wednesday review: Stones equals Gameweek record
Part 9: FPL Thursday review: Pope the top-scoring goalkeeper
Part 10: FPL Saturday review: Grealish breaks 100-point barrier