Team news
Adam Lallana and Davy Propper are ruled out for Brighton, while Neal Maupay (hamstring) will be assessed.
Tariq Lamptey is available having served a one-match suspension.
Danny Ings returned to training on Thursday following a knee injury and could return for Southampton. Nathan Redmond (hamstring) remains a doubt.
Did you know?
Brighton & Hove Albion are looking to go four Premier League matches unbeaten for the first time since a run of five between January and March 2018. They are also targeting their first home win in this season's competition.
Danny Welbeck has been involved in six goals in his last three starts against Southampton in all competitions, with four strikes and two assists. Against no side has he scored more goals in all competitions than he has against Saints, with five.
Southampton have played more PL matches without defeat against Brighton than they have any other side in the competition, with six (W2 D4).
Ralph Hasenhuttl has won 52 per cent of his PL points with Southampton away from home. Of all managers to have taken charge of 50+ PL matches, only Ossie Ardiles has won a higher share on the road, with 56 per cent.
Match officials
Referee: David Coote. Assistants: Darren Cann, Nick Hopton. Fourth official: Graham Scott. VAR: Peter Bankes. Assistant VAR: Sian Massey-Ellis.