Third-placed Manchester City can move to within one point of Leicester City in second if they can end the Foxes' nine-match unbeaten run.
A win for Brendan Rodgers' men would close the gap on leaders Liverpool to seven points ahead of the two sides meeting at King Power Stadium on Boxing Day.
Man City have been boosted by the return to training of Sergio Aguero (groin) and John Stones (hamstring) and both are in contention to face Leicester.
But David Silva (knock) is ruled out, joining the long-term injured Aymeric Laporte (knee), Leroy Sane (knee) on the sidelines.
Brendan Rodgers has declared a "clean bill of health" for Leicester, with no new injuries to report.
Matty James (Achilles) has returned to training but is yet to get any match minutes under his belt as he continues his rehabilitation.
Man City have won four of their last five Premier League meetings with Leicester, losing the other in December last season 2-1 at King Power Stadium.
Man City have won 249 Premier League matches since 1 January 2010. They could become only the second team in English top-flight history to reach 250 victories in a single decade, after Manchester United’s 255 in the 2000s.
Leicester have won their last four Premier League away matches by an aggregate score of 17-1. The Foxes have never previously won five consecutive away matches in the top flight.
Foxes striker Jamie Vardy has the most goals in the Premier League this season, with 16, while Man City’s Kevin De Bruyne has the most assists, with nine. They are the top two players for most goal involvements in the competition (Vardy 19, De Bruyne 15).
Referee: Mike Dean. Assistants: Darren Cann, Dan Robathan. Fourth official: Andy Madley. VAR: Andre Marriner. Assistant VAR: Andy Halliday.