Liverpool have the chance to extend their lead at the top to 11 points as they host bottom club Watford in the first fixture of Matchweek 17.
The Hornets ended a three-match losing streak with a draw against Crystal Palace last time out and would leapfrog Norwich City with a win at Anfield.
Team news
Liverpool's Dejan Lovern has been ruled out after sustaining a muscle injury in the UEFA Champions League.
Jurgen Klopp is also unable to call on Joel Matip, who continues to be sidelined with a knee problem.
Craig Dawson will be available for Watford having recovered from a head injury.
Head coach Nigel Pearson will assess injured duo Roberto Pereyra and Adam Masina, but Jose Holebas is ruled out with an ankle problem.
Did you know?
Liverpool have won their last three Premier League home matches against Watford 6-1, 5-0 and 5-0. No side have won four consecutive home matches by a margin of five or more goals against an opponent in top-flight history.
Mohamed Salah has been involved in seven goals in four Premier League appearances against Watford, while Sadio Mane has contributed to eight goals in five matches against them for Liverpool, and Roberto Firmino has scored or assisted eight in his last six against them.
Liverpool have scored a league-high 10 headed goals this season, more than Watford have scored in total in 2019/20 (nine).
Since winning 1-0 in their first Premier League visit to Anfield in August 1999, Watford have lost their last five away against Liverpool by an aggregate score of 20-1.
Match officials
Referee: Andre Marriner. Assistants: Scott Ledger, Simon Long. Fourth official: David Coote. VAR: Jonathan Moss. Assistant VAR: Andy Halliday.