Antony Evans scored twice as Premier League Cup holders Everton beat Watford 3-0 for their first win in this season's competition.
Matthew Foulds made the breakthrough for the home side at Southport before Evans headed in the second and then wrapped up the victory with a superb free-kick.
The Toffees are now on four points from three matches and move up to second in Group B, above third-placed Watford on goal difference.
See: Everton report
Group E
Alex Dobre and Jake Scrimshaw scored as AFC Bournemouth won 2-0 at south-coast rivals Southampton.
Saints goalkeeper Jack Bycroft saved a penalty from Jaidon Anthony after Dobre's opener, before Scrimshaw put the Cherries top of Group E on seven points, three above their third-placed opponents.
See: Southampton report | AFC Bournemouth report
Mohamed Sankoh struck twice to help Stoke City earn a first PL Cup win as they beat Nottingham Forest 4-0.
Jake Dunwoody and Gabriel Kyeremateng also netted as Stoke moved into second on five points, while Forest are bottom and winless.
See: Stoke report
Group F
Adama Diakhaby scored for Huddersfield Town as they came from behind to draw 1-1 with Liverpool.
A brilliant free-kick from Herbie Kane opened the scoring for the unbeaten Reds, who stay top on seven points.
See: Liverpool report
Group G
Middlesbrough picked up their first win of the Premier League Cup campaign with an emphatic 5-1 victory at Crystal Palace.
Stephen Weame opened the scoring and Stephen Walker added a brace, before further efforts from Isaiah Jones and Ben Liddle for Boro.
See: Palace report | Boro report
Group H
Derby County went top of Group H with an impressive 5-1 win over Birmingham City.
Josh Shonibare put the Rams in front and Jahmal Hector-Ingram scored twice.
An own goal from Joe Bateman gave Birmingham hope, before Jordan Brown and Jayden Mitchell-Lawson wrapped up the victory.
See: Derby report | Birmingham report