The Frenchman is the second most-sold player in the Gameweek, moved on by more than 325,000 managers ahead of Saturday’s 11:30 BST deadline.
Martial has enjoyed an excellent start to the season, producing attacking returns in each of the first three Gameweeks.
Listed as a midfielder in FPL, his appeal has been boosted by his new role as a centre-forward for the Red Devils.
Indeed, prior to confirmation of his absence for this weekend, Martial was the most-bought midfielder in the game with 877,000+ new owners.
The Fantasy forward has played on the left wing this season but may now be shifted into a role up front at St Mary’s Stadium.
And that can boost Rashford's chances of adding to his two goals and one assist.
Owners of Mason Greenwood (£4.5m) will be hoping he can also profit from Martial’s absence.
The 17-year-old sits in 15 per cent of squads but has only featured as a substitute in each of the opening three Gameweeks.