Adam Lallana could feature for Liverpool having fully recovered from a hamstring injury sustained in March.
Emre Can (back) remains out with long-term absentees Joe Gomez (ankle), Alex Oxlade-Chamberlain (knee) and Joel Matip (thigh).
Brighton & Hove Albion have no fresh injury concerns with only Steve Sidwell (ankle) unavailable.
Liverpool are unbeaten in their last 21 home Premier League matches against promoted sides (W16 D5), ever since a 2-1 loss to Blackpool in 2010/11.
If the Reds avoid defeat, it will be the seventh time they have remained unbeaten at home across an entire top-flight campaign, more than any other side.
Mohamed Salah still needs one goal to set a record for most goals in a 38-match PL season. However, the Egyptian has not scored in two consecutive matches for only the second time this season.
Glenn Murray has been directly involved in a goal in all three of his PL meetings with Liverpool, scoring twice and assisting another.
Referee: Kevin Friend
Assistants: Mark Scholes, Sian Massey-Ellis
Fourth official: Mike Jones