Liverpool and Manchester City meet at Anfield tonight in the first leg of the UEFA Champions League quarter-finals.
It is the first time two Premier League clubs have gone head-to-head in the competition for seven years.
But such duels were once common.
Here we look at the past UEFA Champions League encounters between PL clubs.
2003/04 quarter-final: Chelsea v Arsenal
Results: 1-1, 1-2 (agg 3-2 to Chelsea)
Winner's progress: Semi-finals
After Eidur Gudjohnsen and Robert Pires had each scored at Stamford Bridge, Jose Antonio Reyes put Arsenal ahead at Highbury. But Frank Lampard levelled and Wayne Bridge hit a late winner.
2004/05 semi-final: Chelsea v Liverpool
Results: 0-0, 1-0 (agg 1-0 to Liverpool)
Winner's progress: Champions
After a stalemate at Stamford Bridge, Liverpool went through thanks to a fourth-minute goal at Anfield as Luis Garcia’s shot just crossed the line.
2005/06 group stage: Liverpool v Chelsea
Results: 0-0, 0-0
Clubs' progress: Both reached last 16
Defending UCL champions Liverpool were drawn in the same group as Chelsea. Neither match had a goal but both teams qualified with Liverpool topping the group.
2006/07 semi-final: Chelsea v Liverpool
Results: 1-0, 1-0 (agg 1-1, Liverpool win 4-1 pens)
Winner's progress: Runners-up
With each team winning their home leg 1-0, the tie was decided on penalties. Jose Reina denied both Arjen Robben and Geremi, while Liverpool scored all four of their kicks.
2007/08 quarter-final: Arsenal v Liverpool
Results: 1-1, 4-2 (agg 5-3 to Liverpool)
Winner's progress: Semi-finals
After a 1-1 draw at Emirates Stadium, and goals from Abou Diaby, Sami Hyypia, Fernando Torres and Emmanuel Adebayor left the tie at 3-3 in the 84th minute at Anfield.
But Steven Gerrard scored a penalty and Ryan Babel put Liverpool out of sight.
2007/08 semi-final: Liverpool v Chelsea
Results: 1-1, 3-2 (agg 4-3 to Chelsea aet)
Winner's progress: Runners-up
John Arne Riise's late own goal cancelled out Dirk Kuyt's strike at Anfield. It was 1-1 again after 90 minutes at Stamford Bridge but Chelsea won in extra-time thanks to a penalty from Frank Lampard and Didier Drogba.
2007/08 final: Chelsea v Manchester United
Result: 1-1 (Man Utd won 6-5 on penalties)
Cristiano Ronaldo and Lampard swapped first-half strikes in Moscow to bring about penalty shoot-out. After Ronaldo's effort was saved, John Terry slipped to miss the chance to win the trophy.
Edwin van der Sar saved Nicolas Anelka’s spot-kick to secure the trophy for Manchester United.
2008/09 quarter-final: Liverpool v Chelsea
Results: 1-3, 4-4 (agg 7-5 to Chelsea)
Winner's progress: Semi-finals
Torres scored a sixth-minute opener at Anfield but Chelsea responded with two goals from Branislav Ivanovic and another from Drogba.
Fabio Aurelio and Xabi Alonso put Liverpool 2-0 up at Stamford Bridge but Chelsea hit back three times through Drogba, Alex and Lampard, going 6-3 up on aggregate.
Goals from Lucas Leiva and Kuyt meant Liverpool needed only one more to progress but Lampard had the final word for Chelsea.
2008/09 semi-final: Manchester United v Arsenal
Results: 1-0, 1-3 (agg 4-1 to Man Utd)
Winner's progress: Runners-up
After John O'Shea scored the only goal at Old Trafford, Park Ji-Sung and Ronaldo added to United's advantage inside the opening 11 minutes at Emirates Stadium. Ronaldo struck again before a late Robin van Persie consolation.
2010/11 quarter-final: Chelsea v Manchester United
Results: 0-1, 2-1 (agg 3-1 to Man Utd)
Winner's progress: Runners-up
Wayne Rooney struck as Man Utd won 1-0 at Stamford Bridge before Chicharito made it 2-0 on aggregate at Old Trafford. Park and Drogba traded quickfire goals in the 77th minute as Sir Alex Ferguson's side progressed.