Manager Eddie Howe says the Cherries have picked up "a couple of knocks" but did not reveal who might be doubtful.
AFC Bournemouth have never lost a Premier League home match against a promoted side (W6 D1). They have won the last six and scored 21 goals in the process.
The Cherries are looking to win a fourth consecutive PL home match for the first time.
Newcastle United, who beat Manchester United in their last outing, could win a second successive PL match for the first time since September.
Ayoze Perez has scored in both of his PL starts against AFC Bournemouth and struck the winning goal in November 2015. The last Newcastle player to score in their first three starts against the same opponent was Papiss Cisse in November 2015 against Crystal Palace.
Referee: Roger East
Assistants: Simon Beck, Sian Massey-Ellis
Fourth official: James Linington