West Bromwich Albion midfielder Gareth Barry (thigh) is in contention for Sunday's match.
Matt Phillips (hamstring) and Craig Dawson (knee) are closing in on a return, while Nacer Chadli (hip) is back in training, although this weekend will probably be too soon for them to feature.
Manchester United's Eric Bailly will be out for two to three months after the defender had surgery on an injured ankle.
Midfielder Paul Pogba serves the final match of his suspension.
Did you know?
West Bromwich Albion have won three of their eight Premier League matches against Manchester United since Sir Alex Ferguson's retirement at the end of 2012/13, having previously gone 14 against them without a win (D3 L11).
Gareth Barry could make his 36th PL appearance against Man Utd - only Ryan Giggs (38 v Liverpool) has faced an opponent more often in the competition.
Romelu Lukaku has been directly involved in seven goals in six PL starts versus West Brom (four goals, three assists).
No manager has beaten Jose Mourinho more times in the Premier League than Alan Pardew's three.
What the managers say
Alan Pardew: "Our last performance at home [against Crystal Palace] deserved a win. The fans understand the opposition is different this time around but they'll be with us."
See: Pardew on his tactics for Man Utd
Jose Mourinho: "The [West Brom] squad is good, the players are good, the stadium is enthusiastic, the match is difficult."
See: Mourinho: I knew it was not going to be an easy job
Referee: Anthony Taylor
Assistants: Stephen Child, Harry Lennard
Fourth official: Bobby Madley