Here's what to look out for over the next seven days, including the return of the UEFA Champions League and another huge weekend of Premier League action ahead, including Liverpool against Manchester City.
Tuesday
Pep Guardiola will provide the latest team news updates in his press conference ahead of Man City's UEFA Champions League round of 16 second-leg tie at home to Copenhagen.
Wednesday
Man City host Copenhagen looking to continue their 100 per cent record in this season's Champions League, with the match beginning at 20:00 GMT.
Kevin De Bruyne scored one goal and produced two assists to give Guardiola's side a 3-1 advantage following an impressive first-leg win in Denmark.
Elsewhere, find out all the latest team news from Roberto De Zerbi, Jurgen Klopp, David Moyes and Unai Emery ahead of European matches for Brighton, Liverpool, West Ham and Villa on Thursday.
Thursday
Brighton head coach De Zerbi will be reunited with his "big friend", former Italy captain Daniele De Rossi, as the Seagulls face Italian giants Roma in the Europa League round of 16 first-leg tie.
Speaking about De Rossi, who replaced Jose Mourinho as Roma coach in January, De Zerbi said: “I like him, he thinks the same as me about football. He is a passionate person and we are friends, but I hope to win.”
Liverpool travel to the Czech Republic for their first-leg tie against Sparta Prague. The Reds last played in the Czech capital under Kenny Dalglish in 2011.
West Ham face German side Freiburg in their Europa League round of 16 first-leg tie fresh from back-to-back Premier League wins against Brentford and Everton. The Hammers met Freiburg in this season's group stage, winning 2-1 in Germany and 2-0 at London Stadium.
Emery's Villa will head to Amsterdam to face a tough Europa Conference League first leg against Ajax.
Elsewhere, several managers will be holding their press conferences as they provide the latest injury updates ahead of the weekend's Premier League fixtures.
Friday
The winners will be announced for the February Player of the Month, Manager of the Month, Goal of the Month, Save of the Month and Premier League 2 Player of the Month awards.
More managers will address the media ahead of the weekend's fixtures.
Saturday
The Fantasy Premier League deadline for Double Gameweek 28 is at 11:00 GMT.
There are five matches taking place, starting at 12:30 GMT with Manchester United hosting Everton and concluding at 17:30 GMT with a London derby as Arsenal welcome Brentford to Emirates Stadium.
Sunday
The action continues with four more fixtures, starting at Villa, who face fellow top-six contenders Tottenham Hotspur at 13:00 GMT, and finishing with a titanic title showdown between Liverpool and Man City at Anfield at 15:45 GMT.