The dream start for ePremier League new boys Brentford continued as they made it two wins from two by defeating West Ham United 7-2 on aggregate.
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In a tight first leg SamBrwster gained a slender 3-2 advantage on Xbox, before tomsmithh7 put on a masterclass to win 4-0 on Playstation 5.
Goals were in shorter supply in the other Group A match-up, with Brighton & Hove Albion held to a second consecutive draw as both legs against Chelsea finished 1-1.
In a ding-dong affair between Everton and defending ePL champions Manchester City in Group B, the Toffees came through with a 3-2 triumph thanks to Jas Singh.
Everton trailed 2-1 after the first leg, but two second-half goals in the second leg helped consign City to a second straight defeat.
The 2018/19 ePL champion Tekkz continued his impressive form to guide Liverpool into the quarter-finals.
He earned a 4-1 win in the first leg against Burnley and, although Bur_Josh fought back to grab a 2-0 win for the Clarets in the second leg, that wasn't enough.
Crystal Palace were again among the goals as they brushed aside Manchester United, leaving the Red Devils close to an early exit.
NiKSNEB gave the Eagles a 3-0 first-leg lead, and a 2-2 draw in the second leg sealed a second successive win, with Palace scoring 12 goals across the two matches.
There was a surprise result in the other Group C encounter, with 2020/21 ePL runner-up Ollelito losing his tie as Leeds United were defeated 3-2 by Southampton.
Trailing 1-0 after the first leg, Leeds' MHaywxrd could only manage a 2-2 draw against Michael-Fisher20 as Saints made it two wins from three.
The 2019/20 ePL champion Tom Leese helped Tottenham Hotspur to their first win of the tournament as he overcame the side with whom he lifted the trophy, Watford.
Both he and his team-mate HUGE GORILLA earned 3-1 victories to seal the 6-2 aggregate Group D triumph.
📐 𝐏𝐚𝐬𝐬𝐢𝐧𝐠 with 𝐩𝐚𝐜𝐞 and 𝐩𝐫𝐞𝐜𝐢𝐬𝐢𝐨𝐧 🤤— Premier League (@premierleague) March 26, 2022
Spurs get off to the perfect start against Watford!#ePremierLeague | @EASPORTSFIFA pic.twitter.com/8MoiXjMjcT
Another team coming into form are Aston Villa, who secured a second consecutive win as they beat Newcastle United 4-0 on aggregate.
1mpactZ gave Villa a narrow one-goal advantage on Xbox and kyrowley then rattled off three goals in the second leg to wrap up the comfortable win.
Group A: West Ham 2-7 Brentford | Chelsea 2-2 Brighton
Group B: Everton 3-2 Man City | Liverpool 4-3 Burnley
Group C: Crystal Palace 5-2 Man Utd | Southampton 3-2 Leeds
Group D: Aston Villa 4-0 Newcastle | Spurs 6-2 Watford
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See: Your guide to the 2021/22 ePL Grand Finals