Steve Bruce revealed Callum Wilson (hamstring) has trained over the last few days and has a chance of featuring. Jonjo Shelvey and Matt Ritchie are also back in training, but Ryan Fraser is ruled out.
Miguel Almiron arrived back late from international duty and will be assessed, while Martin Dubravka and Paul Dummett are still sidelined.
Chelsea will be without Christian Pulisic and Thiago Silva, but Kai Havertz (illness) has returned to individual training while the Blues are hopeful Ben Chilwell will be fit.
Newcastle have lost only one of their last seven Premier League home matches against Chelsea (W5 D1) and won this fixture last season courtesy of Isaac Hayden's 90th-minute strike.
The Magpies have won two of their last three home league matches, as many as they had in their previous 11 at St James' Park. They are looking to pick up consecutive home league wins for the first time since December 2019.
Chelsea are unbeaten in six PL matches (W3 D3), with only Spurs being on a longer current such run (seven). The Blues have netted at least three goals in five of those six matches.
Timo Werner can become the first player to score in five consecutive appearances for Chelsea in all competitions since Didier Drogba in November 2009, and the fourth German to score in three consecutive Premier League matches after Jurgen Klinsmann, Dietmar Hamann and Leroy Sane.
Referee: Craig Pawson. Assistants: Ian Hussin, Harry Lennard. Fourth official: Robert Jones. VAR: Simon Hooper. Assistant VAR: Stephen Child.