Two of the early pacesetters go head-to-head in a meeting between the second and third-placed teams.
Hosts Leicester City are aiming for a fourth win from their opening five fixtures, after suffering a setback last time out with a 3-0 home defeat to West Ham United.
Aston Villa head to King Power Stadium seeking to maintain their perfect start and having triumphed 7-2 against champions Liverpool in their last outing.
Wesley Fofana could make his Leicester debut after Caglar Soyuncu sustained an abductor injury over the international break.
James Maddison (hip) is in contention, while Jamie Vardy (calf), Jonny Evans (abdominal) and Dennis Praet (knee) will be assessed. Wilfred Ndidi (adductor) and Ricardo Pereira (ACL) remain out.
Dean Smith reports no fresh injury concerns for Aston Villa.
Leicester have won four of their last five Premier League meetings with Aston Villa.
The Foxes scored eight Premier League goals against Villa last season, with Jamie Vardy netting four of them.
Villa are looking to win their opening four league matches of a season for the first time since 1930/31, when they finished second in the top flight.
Since the start of last season, Ollie Watkins has scored more league goals in England’s top two tiers than anyone else, with 29, including play-offs.
Referee: Jonathan Moss. Assistants: Harry Lennard, Dan Robathan. Fourth official: Darren England. VAR: Graham Scott. Assistant VAR: Timothy Wood.