Burnley can climb above Sheffield United into eighth place, if the Blades lose to Southampton, and earn their most points in a single Premier League campaign.
Brighton & Hove Albion secured their Premier League safety in midweek following a 0-0 draw with Newcastle United.
Team news
Ashley Barnes, Ben Mee, Matt Lowton, Jack Cork and Charlie Taylor have all been ruled out for the hosts.
The Seagulls have a full squad apart from long-term absentee Jose Izquierdo (knee surgery) and Steven Alzate.
Did you know?
If Burnley avoid defeat they will set a club record points total for a Premier League campaign.
Chris Wood has scored 13 Premier League goals this season, the most by a Burnley player in a single top-flight campaign since 1975/76.
Since their first Premier League campaign in 2017/18, no side has more 0-0 draws in the competition than the 11 recorded by Brighton.
With 10 goals, Seagulls' striker Neal Maupay is the highest Premier League goalscorer this season among players who haven’t scored more than once in a match.
Match officials
Referee: Jonathan Moss. Assistants: Edward Smart, Richard Wild. Fourth official: Jeremy Simpson. Replacement official: Graeme Fyvie. VAR: Darren Bond. Assistant VAR: Dan Robathan.