Champions Liverpool can complete an unbeaten season in Premier League home matches before they lift the Trophy on the Kop.
A point for Chelsea would cement a top-four finish with a match to spare.
Team news
James Milner is in training and could feature for Liverpool, but the Reds will be without Jordan Henderson (knee) and Joel Matip (foot).
N'Golo Kante (hamstring) remains sidelined but Frank Lampard has reported no other injury concerns.
Did you know?
Liverpool are unbeaten in 58 Premier League home matches, winning 17 of their 18 at Anfield so far this season. If they avoid defeat here, it will be the ninth time they have remained unbeaten at home across an entire top-flight campaign, three more than any other side.
If Roberto Firmino does not score against Chelsea he will set a record for the most goals in a season all coming away from home, with eight.
Chelsea have won 18 of their 44 Premier League matches against sides starting the day top of the table, more than any other side in the competition.
Olivier Giroud has scored six goals in his last 10 Premier League matches for Chelsea, more than he had in his previous 46 for the Blues, with five.
Match officials
Referee: Andre Marriner. Assistants: Scott Ledger, Richard West. Fourth official: Lee Mason. Replacement official: Paul Hodskinson. VAR: Stuart Attwell. Assistant VAR: Stephen Child.
