Sixth-placed Wolverhampton Wanderers are seeking to extend their 11-match unbeaten run.
A fourth win in five matches for Jose Mourinho since taking charge at Tottenham Hotspur would take his side above Wolves in the table.
Team news
Wolves remain without Willy Boly (ankle), while Morgan Gibbs-White (back) is unlikely to be available.
Harry Winks (ankle) returned to training with Spurs this week and could be in contention. Harry Kane, Dele Alli, Jan Vertonghen and Serge Aurier are available having been rested for the midweek UEFA Champions League match against Bayern Munich.
Erik Lamela (hamstring), Hugo Lloris (elbow), Michel Vorm (calf), Ben Davies (ankle) and Tanguy Ndombele (groin) continue their rehabilitation.
Did you know?
Wolves beat Spurs 3-1 at Wembley in their last Premier League meeting in December 2018. They’ve not won consecutive matches against the north London club since completing the league double over them in 2009/10.
Since the start of last season, Wolves have taken more points against the 2018/19 top six than any other side who finished outside of these places last term, with 21.
Spurs have only lost one of their five Premier League away matches against Wolves (W3 D1), suffering a 1-0 defeat in February 2010.
Harry Kane has scored nine Premier League goals this season, and could become the first player to score 10 in six consecutive top-flight campaigns for Spurs since Robbie Keane, who did so between 2002/03 and 2007/08.
Match officials
Referee: Stuart Attwell. Assistants: Dan Robathan, Darren Cann. Fourth official: Simon Hooper. VAR: David Coote. Assistant VAR: Stephen Child.