Watford are looking for a first win in four Premier League matches as they host a side lying just one place and one point below them.
Marco Silva's Toffees are aiming to avoid a third straight defeat.
Watford midfielder Abdoulaye Doucoure (knee) and winger Roberto Pereyra (hamstring) face late fitness tests, but Kiko Femenia (hamstring), Sebastian Prodl (knee) and Isaac Success (hamstring) are out.
Defenders Phil Jagielka (undisclosed), Yerry Mina (ankle) and Leighton Baines (ribs) are out for Everton.
After losing their first two PL home matches against Everton, Watford are now unbeaten in three, winning the last two in a row.
Watford can secure a third successive home win over a single opponent for the first time in the Premier League.
The Hornets will be seeking a return to their early-season form at Vicarage Road. After winning their opening three PL home matches this season, they have picked up just eight points from a possible 27 since.
Everton are looking to win a second consecutive PL away fixture for the first time since September 2016.
Referee: Lee Probert
Assistants: Adrian Holmes, Derek Eaton
Fourth official: Roger East