Leaders Liverpool are targeting their 11th victory in 12 Premier League matches, while Crystal Palace are bidding to bounce back after their home defeat by Watford.
Team news
Liverpool are monitoring the fitness of Trent Alexander-Arnold and Georginio Wijnaldum (both knee), while Dejan Lovren (thigh) and Joe Gomes (ankle) are out.
Adam Lallana has returned to training and Joel Matip (collarbone) is fully fit.
Crystal Palace are without two of their goalkeepers. Wayne Hennessey (thigh) and Vicente Guaita (calf) are injured.
However, Roy Hodgson has no other new injury concerns.
Did you know?
Liverpool are looking to win a seventh consecutive PL home match for the first time since January 2014.
Sadio Mane has scored more PL goals against Crystal Palace than any other side, with six, and could now strike in a fourth consecutive PL match against the same opponent for the first time.
Palace have won three of their last four PL visits to Liverpool, although they were defeated last time.
The Eagles are looking to win a third consecutive PL away match within the same season for the first time since February 2015.
Referee: Jonathan Moss
Assistants: Marc Perry, Andy Halliday
Fourth official: Andre Marriner