League leaders Liverpool remain unbeaten this season and have won their last eight Premier League matches.
Arsenal, meanwhile, have two wins from their last five matches and draw at Brighton last time out.
Team news
Liverpool will be without James Milner (hamstring) but Alberto Moreno (back) is available to play.
Dominic Solanke (muscle), Joe Gomez (ankle), Joel Matip (collarbone) and Alex Oxlade-Chamberlain (knee) are all out.
For the visitors Shkodran Mustafi (hamstring) is in contention to return for the trip to Anfield but Nacho Monreal (muscular) is a doubt.
Hector Bellerin (calf), Henrikh Mkhitaryan (metatarsal), Kostas Mavropanos (groin), Rob Holding (knee), Emile Smith-Rowe (hip) and Danny Welbeck (ankle) are all out.
Did you know?
This will be the 227th meeting between these two teams in all competitions. Liverpool have been victorious 86 times compared to Arsenal's 79. There have been 61 draws.
Arsenal are without a win in their last five trips to Anfield, conceding two or more goals in each match and 17 in total.
Liverpool have gone seven matches unbeaten against Arsenal in all competitions (W3 D4). The last time they had a run longer was in February 200 which lasted 14 matches.
Liverpool's Roberto Firmino has been directly involved in eight goals in his last six PL matches against Arsenal scoring five goals and three assists. Only Robbie Fowler, with nine goals, has netted more PL goals against Arsenal for Liverpool than Firmino.
Match officials
Referee: Michael Oliver
Assistants: Stuart Burt, Simon Bennett
Fourth official: Jonathan Moss
