Unbeaten leaders Manchester City are targeting an eighth straight Premier League victory as they visit fourth-placed Chelsea, who are aiming to respond after losing at Wolverhampton Wanderers.
Chelsea have no serious injuries and everyone is available for selection.
The PL champions must make do without Sergio Aguero (muscle), Kevin De Bruyne, Benjamin Mendy, Eliaquim Mangala (all knee) and Claudio Bravo (Achilles).
Man City have a chance to secure a second successive top-flight victory at Chelsea for the first time since January 1955.
City also have an opportunity to beat Chelsea for the fourth time in a row in all competitions, something they have never done before. This is the 161st meeting between the teams.
Pep Guardiola's side are unbeaten in their last 14 PL away matches. City have never gone 15 without defeat on the road in the top flight.
Leroy Sane has contributed a goal or assist in his last eight PL starts this season, striking six times and assisting a further five goals.
Referee: Michael Oliver
Assistants: Stuart Burt, Simon Bennett
Fourth official: Andre Marriner