Manchester United will aim to bounce back from their derby defeat by Manchester City and improve on their eighth-placed position.
Visiting Crystal Palace are seeking a first victory in eight Premier League matches.
Team news
Man Utd have no new injury problems after Marouane Fellaini, Paul Pogba, Anthony Martial and Marcus Rashford were all passed fit.
Striker Romelu Lukaku should be able to play but Luke Shaw is suspended.
Crystal Palace trio Mamadou Sakho, Wilfried Zaha and James Tomkins are all available.
Connor Wickham, Christian Benteke and Scott Dann are working on their recoveries but will not be fit for the weekend.
Did you know?
Man Utd have played 18 PL matches against Crystal Palace without ever losing, the highest number in the competition for a team who have never been defeated by an opponent.
Juan Mata, who has scored in two of his three PL home matches for United against Palace, has produced 49 goals and 49 assists in the competition.
Romelu Lukaku has scored in six of his last eight PL appearances against Palace, including both for Man Utd last season.
Jose Mourinho has only lost one of his 51 PL home matches kicking off at 3pm on a Saturday, but that defeat came against Palace when he was Chelsea manager in August 2015.
Referee: Lee Mason
Assistants: Harry Lennard, Marc Perry
Fourth official: Anthony Taylor
