Cardiff City are hunting for their first victory of the season, while Arsenal are aiming to build momentum after getting their first win against West Ham United.
Cardiff City expect Nathaniel Mendez-Laing to be out for three months with a posterior cruciate ligament injury.
Junior Hoilett (groin) is doubtful but will be given every chance to play. Aron Gunnarrsson (knee) is back in training.
Arsenal say none of Sead Kolasinac (knee), Ainsley Maitland-Niles (fibula), Carl Jenkinson (ankle) or Laurent Koscielny (Achilles) are expected to train until October at the earliest.
Mesut Ozil has recovered from illness and is fit and available for selection.
Cardiff have the chance to earn their first victory over Arsenal in 14 matches in all competitions (D5 L8). They last beat the Gunners in February 1961, winning 3-2 away.
Neil Warnock won his last home match against Arsenal, triumphing 1-0 with Sheffield United in the Premier League in December 2006. His last home defeat against them came in September 1993 as Huddersfield Town manager, when an Ian Wright hat-trick inspired Arsenal to a 5-0 win in the League Cup.
Four of Arsenal’s five PL goals against Cardiff have come in the final five minutes.
Matteo Guendouzi could become only the fourth teenager to start each of Arsenal’s first four matches of a PL season, after Nicolas Anelka (1998/99), Cesc Fabregas (2004/05 and 2006/07) and Johan Djourou (2006/07).
Referee: Anthony Taylor
Assistants: Gary Beswick, Adam Nunn
Fourth official: David Coote