Brighton & Hove Albion will be without the suspended Davy Propper as well as long-term absentees Steve Sidwell (ankle) and Isaiah Brown (knee).
Danny Rose (calf) is a doubt for Tottenham Hotspur, while Harry Winks (ankle) remains sidelined.
Did you know?
Brighton & Hove Albion have only lost four Premier League home matches this season, but three of those have come against sides currently sitting in the top six places.
Glenn Murray has not scored in his last two PL home matches. He has not failed to score in three consecutive fixtures at the Amex Stadium since his first three appearances there this season.
Tottenham Hotspur are unbeaten in their last 34 PL matches against promoted opposition, winning the last 16 in a row. Only Chelsea have ever had a longer unbeaten run against promoted sides: 63 between 2001 and 2011.
Since the start of 2014/15, Harry Kane has scored 22 goals in 20 matches against promoted sides. He has also scored a hat-trick against one of them in each of the previous three seasons: Leicester City in 2014/15, AFC Bournemouth in 2015/16 and Hull City in 2016/17.
Club previews
Brighton: Hughton taking positives from Wembley effort
Spurs: Pochettino looking forward to Hughton reunion
Referee: Kevin Friend
Assistants: Matthew Wilkes, Mark Scholes
Fourth official: Lee Probert
