Crystal Palace defenders Martin Kelly and Jeffrey Schlupp are back in contention while new signing Diego Cavalieri is available, but Roy Hodgson is still faced with a lengthy injury list.
Ten senior players are out of action and loanee Timothy Fosu-Mensah is also unable to face his parent club.
Manchester United have an unchanged squad and will again be without defenders Daley Blind (ankle), Phil Jones and Marcos Rojo (both knocks).
Ander Herrera (thigh) and Marouane Fellaini (knee) are also out of action, while Zlatan Ibrahimovic (knee) will decide when he feels fit and confident enough to return.
Did you know?
This is Crystal Palace’s first Monday PL match since they beat Arsenal 3-0 in April last season. They have a better win rate on this day of the week than any other: 35%, having won eight matches out of 23.
Crystal Palace haven’t won any of their 17 PL meetings with Manchester United, the most a team has played another without a single victory in the competition (D3 L14).
Anthony Martial and Romelu Lukaku have combined for six PL goals this season (three assists each to each other). No Man Utd partnership has had more in a single campaign, with Martial/Wayne Rooney in 2015/16 the last duo to get this many.
Paul Pogba has scored in both of his PL matches against Palace. They are the only team he has scored against both home and away in the competition.
Club previews
Crystal Palace: Hodgson: The latest on Zaha
Manchester United: Key quotes: press conference
Referee: Neil Swarbrick
Assistants: Scott Ledger, Richard West
Fourth official: Lee Mason