Brighton & Hove Albion defender Dan Burn will train on Friday and could be available.
Adam Webster, Tariq Lamptey, Solly March and Aaron Connolly remain sidelined.
Newcastle United's Miguel Almiron may be in contention while Callum Wilson and Allan Saint-Maximin are on track to return after the international break.
Brighton are unbeaten in all seven of their Premier League meetings with Newcastle (W3 D4).
The Seagulls are seeking their first league double over Newcastle since 1978/79.
Newcastle have picked up just nine PL points since the turn of the year. Only Southampton have fewer, with seven.
Newcastle’s last two PL goals have been scored by Jamaal Lascelles. The defender has scored two in his last three appearances, as many as in his previous 98 in the competition.
Referee: Anthony Taylor. Assistants: Gary Beswick, Adam Nunn. Fourth official: Kevin Friend. VAR: Stuart Attwell. Assistant VAR: Stephen Child.