Leeds United's Rodrigo is a major doubt due to the muscle problem that forced him off in the 3-1 victory at Leicester City.
But Patrick Bamford (dead leg) and Raphinha (muscle injury) are only minor doubts.
Fabian Delph is back in contention for Everton. However, goalkeeper Jordan Pickford has been ruled out with a rib injury, and Allan and Jean-Philippe Gbamin remain sidelined.
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Following their 1-0 win at Goodison Park in the reverse fixture, Leeds are looking to complete their first Premier League double over Everton. They have lost only one of their last 37 top-flight home meetings with the Toffees (W27 D9).
Patrick Bamford has been directly involved in 15 goals in his 20 PL appearances for Leeds this season, scoring 11 times and providing four assists. Only Tony Yeboah has had a hand in more goals in their first 20 PL appearances for the club, with 17.
Everton are looking to win four consecutive PL away matches for the first time.
In his first nine PL outings this season, Everton’s Dominic Calvert-Lewin scored 10 goals from 29 shots for a conversion rate of 34 per cent. In his subsequent nine league appearances, he’s scored just once from 19 shots, with a five per cent conversion rate.
Referee: Michael Oliver. Assistants: Stuart Burt, Simon Bennett. Fourth official: Darren England. VAR: Chris Kavanagh. Assistant VAR: Daniel Cook.