Team news
Southampton will again be without Danny Ings (knee) and Nathan Redmond (hamstring).
Jesse Lingard, Victor Lindelof, Aaron Wan-Bissaka and Marcus Rashford could be available for Manchester United.
Scott McTominay and Paul Pogba both missed training on Friday and are doubts, while Luke Shaw remains sidelined.
Did you know?
Southampton have won their last three PL home matches, triumphing 2-0 each time. They last won four in a row at St Mary’s back in May 2016.
Saints are unbeaten in seven PL matches (W5 D2), with only Spurs being on a longer current run. Their last eight-match sequence came between September and November 2013 under Mauricio Pochettino.
Man Utd are aiming to win an eighth successive top-flight away match for the first time ever.
Bruno Fernandes has scored the winner in all four of Man Utd's PL victories this season.
Match officials
Referee: Jonathan Moss. Assistants: Marc Perry, Dan Robathan. Fourth official: Graham Scott. VAR: Martin Atkinson. Assistant VAR: Timothy Wood.