Everton are aiming to bounce back after their late 3-2 defeat at Brighton & Hove Albion, which leaves them two points above the relegation zone in 16th place.
Tottenham Hotspur are looking for a first win in four matches after dropping to 11th.
Everton are without Jean-Philippe Gbamin (quadriceps) and Bernard (knee) but Yerry Mina could be fit to face Spurs after training on Friday morning.
The visitors will be without midfielder Erik Lamela (hamstring), goalkeeper Hugo Lloris (elbow) and defender Danny Rose (suspended).
However, centre-back Jan Vertonghen (hamstring) could play should he pass a fitness test.
Spurs and Everton are meeting in a Premier League match while both starting the day in the bottom half for the first time since April 2004, when David Moyes’s Toffees beat David Pleat’s visitors 3-1 at Goodison Park.
Everton have lost their last two home matches against Spurs 3-0 and 6-2. They have never lost three consecutive top-flight home fixtures by at least three goals against an opponent.
Spurs are targeting their first victory in 12 away matches. They are on their longest such winless run since a sequence of 14 between May 2000 and January 2001 under George Graham.
Christian Eriksen has scored in his last four appearances against Everton and has five goals in total against the Toffees in the competition. Only against Swansea has he netted more, with six.
Referee: Martin Atkinson. Assistants: Lee Betts, Peter Kirkup. Fourth official: David Coote. VAR: Anthony Taylor. Assistant VAR: Adam Nunn.