Wolverhampton Wanderers damaged 10-man Manchester United's top-four aspirations with a 2-1 comeback victory at Molineux.
Ole Gunnar Solskjaer's side were targeting third place in the table and were rewarded for early pressure when Fred's pass enabled Scott McTominay to turn and arrow a long-range effort into the far-left corner after 13 minutes for his first PL goal.
But 12 minutes later, Wolves were level when a defensive error led to Raul Jimenez clipping in a pass for Diogo Jota, who struck past David De Gea.
Rui Patricio kept out McTominay's close-range header before Man Utd's Ashley Young was sent off after receiving a second yellow card.
And Wolves claimed the three points with 13 minutes left to play when United defender Chris Smalling deflected the ball past De Gea, while Ivan Cavaleiro struck the crossbar late on.
Man Utd stay in fifth place on 61 points, two behind third-placed Arsenal having played an extra match. Wolves remain seventh on 47 points.
Wolves: 13 Apr v Southampton (A)
Man Utd: 13 Apr v West Ham (H)